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Pharmachologic effect Domperidone (active ingredient) has an antiemetic effect, soothes hiccups. Increases the muscle tone of the stomach and intestines, accelerates gastric emptying. Indications for use Feeling of fullness in the stomach, bloating and pain in the epigastric region, belching, flatulence, nausea, vomiting, heartburn. A specific indication is nausea and vomiting caused by dopamine agonists when used in the treatment of Parkinson's disease. Pediatric pathologies directly related to hernia and defective function of the lower esophageal sphincter. Dosage and administration Children under 12 years of age are prescribed 0.3 mg per 1 kg of body weight, repeating if necessary 3-4 times a day.

Adults and children over 12 years of age weighing 35 kg or more with chronic dyspepsia are prescribed 10 mg 3 times a day and, if necessary, at bedtime.

With severe nausea and vomiting, it is prescribed at a dose of 20 mg 3-4 times a day before meals and at bedtime. Tablets are recommended to be taken 15-30 minutes before meals. When eating, the absorption of the drug is slightly reduced. In renal insufficiency, it is recommended to reduce the frequency of taking the drug.

After that, the patient's condition should be assessed and a decision should be made on the need for further treatment. There have been isolated cases of intestinal spasms, which quickly pass.

Do not use the drug

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if stimulation of the motor function of the stomach can be dangerous, for example, with gastrointestinal bleeding, mechanical obstruction or perforation of one of the gastrointestinal tract.

It is also contraindicated in patients with prolactin-secretory pituitary tumor (prolactinoma).

Do not prescribe the drug to patients with impaired liver function. Overdose Manifested by drowsiness, disorientation and extrapyramidal disorders, especially in children. In case of an overdose, gastric lavage, the use of activated charcoal, patient observation, supportive and symptomatic therapy are recommended.

For the correction of extrapyramidal disorders, anticholinergic drugs, antiparkinsonian or antihistamines with anticholinergic activity may be effective.

Pharmachologic effect Enhances gastrointestinal motility, has an antiemetic effect.

Indications for use Relief of gastrointestinal symptoms of functional non-ulcer dyspepsia (chronic gastritis), namely: bloating; feeling of rapid satiety; pain and discomfort in the upper abdomen; anorexia; heartburn; nausea; vomit. Dosage and administration Adults are prescribed orally 1 tablet of the drug 50 mg 3 times a day before meals. Side effects Allergic reactions, dizziness, headache, tremor, diarrhea, constipation, abdominal pain, increased salivation, nausea, jaundice.

Contraindications Hypersensitivity to itopride; During pregnancy and breastfeeding; conditions in which an increase in the contractile activity of the gastrointestinal tract can be harmful. Overdose Cases of overdose in humans are not described.

Antiemetic drugs Avioplant Analogues Peppermint tablets, Peppermint leaves, Peppermint tincture, Peppermint oil.

Pharmachologic effect It has an antiemetic effect, stimulates the secretion of saliva, gastric juice, bile, normalizes digestion, enhances gastrointestinal motility, and prevents flatulence.

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