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Dosage and administration Adults and children over 10 years of age are prescribed 5-10 mg; children 4–10 years old - 2.5–5 mg; children under 4 years of age are recommended to dose at the rate of 1 drop per 2 kg of body weight. Side effects Bloating,
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increased bowel contractions, diarrhea.Contraindications Hypersensitivity to the components of the drug, intestinal obstruction, abdominal pain of unknown origin, acute surgical pathology of the abdominal organs, dehydration. When taken in high doses, diarrhea, intestinal cramps and significant loss of potassium and other electrolytes are observed. Like other laxatives, prolonged overdose leads to chronic diarrhea and abdominal pain, hypokalemia. Dufalac Analogues Medulak, Laktuvit, Normolact, Transulose, Depurax, Dufalac fruit, Diagnol, Moviprep.
Pharmachologic effect Lactulose has a laxative, hyperosmotic, hypoammoniemic, stimulating intestinal motility effect, normalizes the intestinal microflora, improves the absorption of phosphates and calcium salts, promotes the excretion of protein breakdown products, is a nutrient medium for beneficial intestinal microflora, promotes its development and reproduction.
The effect develops 24-48 hours after administration. Indications for use Chronic and episodic constipation, postoperative atonic constipation, pain syndrome after removal of hemorrhoids, hepatic encephalopathy, liver failure, hepatic coma and precoma, chronic active hepatitis, hyperammonemia, intoxication of various etiologies, intestinal dysbacteriosis, putrefactive dyspepsia, salmonella carriage. Dosage and administration With constipation, pain after removal of hemorrhoids, putrefactive dyspepsia is prescribed according to the scheme.
Children under 1 year: 5 ml per day (1 tsp); children 1–6 years old: 5–10 ml - Minomycin 100mg, (Minocycline) online Antibiotics 50mg Buy per day (1–2 tsp); children over 6 years old: 15 ml per day (1 tablespoon); adults: 15–45 ml per day (1–3 tablespoons). Children under 1 year: 5 ml per day (1 tsp); children 1–6 years old: 5–10 ml per day (1–2 tsp); children over 6 years old: 10 ml per day (2 tsp); adults: 15 ml per day (1 tablespoon).
The course of treatment ranges from 1-4 weeks to 3-4 months. With salmonella carriers, 5 ml (1 tsp) 3 times a day are prescribed in the first 10-12 days, after a week break, 5 ml (1 tsp) 5 times a day for 10-12 days. In case of liver failure, coma and precoma, encephalopathy, as well as chronic hepatitis, hyperammonemia, intoxications of various etiologies, dysbacteriosis, 30-60 ml (2-4 tablespoons) are prescribed orally 3 times a day, then a maintenance dose of 10 -25 ml (2-5 tsp) 2-3 times a day. When taken orally, the drug can be diluted with water or juice, with the exception of grapefruit. Side effects Flatulence and increased gas formation (disappear on their own after 2-3 days after the start of treatment), in the treatment of hepatic encephalopathy - transient diarrhea, nausea, intestinal cramps.
Contraindications Galactosemia, intestinal obstruction, hypersensitivity to lactulose, rectal bleeding.