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calcium gluconate Analogues Calcium gluconate stabilized, Calcium gluconate fruit, Calcium gluconate-Darnitsa, Calcium gluconate-Darnitsa (stabilized), Calcium gluconate-Health, Calcium gluconate-Health (stabilized), Calcium glycerophosphate.
Pharmachologic effect Calcium ions take part in the transmission of nerve impulses, contraction of smooth and striated muscles, myocardium, blood coagulation processes; necessary for the formation of bone tissue, the functioning of other organs and body systems.
Indications for use It is used for hypoparathyroidism, increased elimination of calcium from the body (in particular with prolonged immobilization), allergic reactions, to reduce the permeability of the vascular wall in various pathologies, hepatitis, toxic liver damage, nephritis, eclampsia, hyperkalemic form of paroxysmal myoplegia, skin diseases, bleeding, in as an antidote for poisoning with magnesium salts, oxalic acid and its soluble salts, as well as soluble salts of fluoric acid.
Dosage and administration In / in and / m adults are administered 5–10 ml of 10% solution, depending on the indications and the patient's condition - daily, after 1 or 2 days.
It is not recommended to administer intramuscularly to children due to the possible development of tissue necrosis at the injection site. In / in, depending on age, children are administered from 1 to 5 ml of 10% solution of
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calcium gluconate.The solution is heated to body temperature before administration; injected slowly over 2-3 minutes. Inside prescribed before meals: adults - at a dose of 1-3 g 2-3 times a day, children under 1 year - 0.5 g, 2-4 years - 1 g, 5-6 years - 1- 1.5 g, 7-9 years old - 1.5-2 g each, 10-14 years old - 2-3 g each.
Side effects Sometimes with parenteral administration, nausea, vomiting, diarrhea, bradycardia, which usually pass quickly, may occur. Contraindications Tendency to thrombosis, hypercalcemia, severe atherosclerosis.
Cocarboxylase-forte Analogues Cocarboxylase hydrochloride.
Pharmachologic effect Coenzyme of thiamine (vitamin B1). It is part of the carboxylase enzyme, which catalyzes the carboxylation and decarboxylation of alpha-keto acids. In medical practice, cocarboxylase hydrochloride is used. Indications for use Acidosis and precoma in diabetes mellitus.
Disorders of cardiovascular activity (changes in heart rate, extrasystole, bigeminia, paroxysmal tachycardia) and coronary circulation. In cardiovascular diseases, a single dose for adults is 0.05–0.1 g, daily dose is 0.05–0.2 g.
In diabetes mellitus, the daily dose for adults is 0.075–1 g.
Side effects Allergic reactions: urticaria, pruritus. With i / m administration, hyperemia, itching, swelling at the injection site.
Overdose Symptomatic treatment aimed at normalizing the activity of breathing and the cardiovascular system; cancellation of cocarboxylase.
Cormagnesin Analogues Biolectra magnesium fortissium, Panangin solution, Panangin tablets, Asparkam, Asparkam-Health, Asparkam-Farmak, Potassium and magnesium asparaginate.
Pharmachologic effect Cormagnesin is a magnesium preparation. Magnesium is a macronutrient, an important intracellular cation. Magnesium is involved in reactions involving more than 300 enzymes, regulation of cell permeability and neuromuscular transmission.
Magnesium is necessary for many energy processes, is involved in the metabolism of proteins, fats, carbohydrates and nucleic acids, and is a natural physiological calcium antagonist.
Magnesium controls the normal functioning of myocardial cells; participates in the regulation of its contractile function. Indications for use Magnesium deficiency, if this is the cause of impaired muscle activity and oral treatment is not possible; preeclampsia and eclampsia; acute myocardial infarction with magnesium deficiency, if thrombolytic therapy is possible and not contraindicated; coronary spasms associated with magnesium deficiency; cardiac arrhythmia, in particular paroxysmal ventricular tachycardia associated with magnesium deficiency, or such that arose as a result of treatment with digitalis of multifocal atrial tachycardia in case of magnesium deficiency.
Dosage and administration The daily dose depends on the magnesium deficiency in the patient.